Insertion of two pyrene moieties into oligodeoxyribonucleotides for the efficient detection of deletion polymorphisms.
نویسندگان
چکیده
For the detection of deletion polymorphisms, two pyrene moieties are tethered to an oligodeoxyribonucleotide (ODN) on both sides of the intervening base; one- and two-base deletions can be selectively detected by the strength of the excimer emission.
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عنوان ژورنال:
- Chemical communications
دوره 26 شماره
صفحات -
تاریخ انتشار 2006